My configuration makes me really sad but it works well for us. We started out with a dodge caravan. The middle seat was a bench and we put the twins there. Then we put DD (18 mos at the time) in the far back and could reach her very well from the opening left from the bench. DS also sat back there but he was old enough that he buckled himself... once the twins got old enough that we wanted to be out on the move, I found that the caravan had NO storage at all. We live far away from shopping and could hardly fit a medium sized costco trip in the car with us once you take into account all of the diapers, extra clothes, and double stroller. By the time they were 1, we had sold the caravan and bought an old Suburban. BTW, I never in a million years thought I would ever own one but I tell ya, we defiantly fill it!
Now in the suburban, it has a 70/30ish split in the middle row so I leave the 30 down most of the time and we use the same configuration as the minivan. There is plenty of room for big britax carseats, a double stroller, and a decent trip (camping/shopping). It is harder to get DD in the back but still very reasonable. And before I knew it, she is almost ready to be buckling herself in...
DS 7, DD 3, twin DDs 19 mos
Tassy mom to DS(13), DD(8), and twin DDs (7)