Ebola vaccine trial proves 100% successful in Guinea - Mothering Forums

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#1 of 1 Old 07-31-2015, 09:17 AM - Thread Starter
 
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Ebola vaccine trial proves 100% successful in Guinea

http://www.theguardian.com/world/201...sful-in-guinea

This is obviously not a vaccine that the vast majority of people would ever need but how promising and exciting for people that live in at risk countries!

"A vaccine against Ebola has been shown to be 100% successful in trials conducted during the outbreak in Guinea and is likely to bring the west African epidemic to an end, experts say.

The results of the trials involving 4,000 people are remarkable because of the unprecedented speed with which the development of the vaccine and the testing were carried out.

Scientists, doctors, donors and drug companies collaborated to race the vaccine through a process that usually takes more than a decade in just 12 months.

The “gold standard” approach would be to take a population at risk of Ebola and vaccinate half of them while giving the other half a placebo. Instead, the researchers used a “ring” design, similar to that which helped prove the smallpox vaccine worked in the 1970s.

When Ebola flared up in a village, researchers vaccinated all the contacts of the sick person who were willing – the family, friends and neighbours – and their immediate contacts. Children, adolescents and pregnant women were excluded because of an absence of safety data for them. In practice about 50% of people in these clusters were vaccinated.

To test how well the vaccine protected people, the cluster outbreaks were randomly assigned either to receive the vaccine immediately or three weeks after Ebola was confirmed. Among the 2,014 people vaccinated immediately, there were no cases of Ebola from 10 days after vaccination - allowing time for immunity to develop - according to the results published online in the Lancet medical journal (pdf). In the clusters with delayed vaccination, there were 16 cases out of 2,380."

What do you think about how they tested the vaccine? Do you think fast-tracking it was a good idea in these circumstances? I know this isn't the "debate" section but the way this was conducted is pretty unprecedented for modern vaccine trials and wondered what you guys thought since I am sure there are going to be some criticisms on the way this was carried out.
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Last edited by teacozy; 07-31-2015 at 09:20 AM.
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