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#1 of 9 Old 06-11-2010, 12:28 PM - Thread Starter
 
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Last time I was on it was 3 years ago, but I remember I had to wean myself because if I just stopped taking it I felt sick. Did anyone else have to do that?

And I find myself needing to take two doses a day instead of one - if I head off with a zofran at say 3AM, I am okay the rest of the day, only maybe vomiting once after it wore off, but now I find myself needing 2 a day. Not sure if it's because my m/s is hitting it's peak (I am almost 10 weeks) or if I just need more to get by because I am building a tolerance. Last pregnancy I could get by with just one a day for all 26 weeks. Right now because of insurance and limited pill refills, I am splitting 8mg in half and only taking 4 mg a day to last me longer

Any thoughts?

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#2 of 9 Old 06-11-2010, 04:16 PM
 
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Originally Posted by lillymonster View Post
Last time I was on it was 3 years ago, but I remember I had to wean myself because if I just stopped taking it I felt sick. Did anyone else have to do that?

And I find myself needing to take two doses a day instead of one - if I head off with a zofran at say 3AM, I am okay the rest of the day, only maybe vomiting once after it wore off, but now I find myself needing 2 a day. Not sure if it's because my m/s is hitting it's peak (I am almost 10 weeks) or if I just need more to get by because I am building a tolerance. Last pregnancy I could get by with just one a day for all 26 weeks. Right now because of insurance and limited pill refills, I am splitting 8mg in half and only taking 4 mg a day to last me longer

Any thoughts?
It is definitely habit-forming. I had to take 3 a day, exactly 8 hrs apart, and by hour 7, I'd be nauseous again. Finally at about 14 weeks, I decided to go cold-turkey, and I just stopped suddenly. I was super-sick for 2 days, and then fine.

DS1 2004 ~ DS2 2005 ~ DD1 2008 ~ DS3 2010 ~ DD2 due Dec. 2014
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#3 of 9 Old 06-11-2010, 04:27 PM
 
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zofran is definately very dependent on having a constant steady stream thats why its so good at working. I have found that at my peak of hyperemesis I had to do 8mg every 8 hrs exactly on time to keep my blood levels constant. For me that was the key to it working. as I have gotten better I have had to taper to every 12 hrs and slowly move my dosage down to 4 and now I only take it for my *waking* hrs. But yeah I feel different almost within 30 min of taking the pill, I think it is somewhat habit forming in a way.
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#4 of 9 Old 06-11-2010, 05:06 PM
 
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But yeah I feel different almost within 30 min of taking the pill, I think it is somewhat habit forming in a way.
It is definitely habit-forming. It is given to opiate addicts to ease withdrawal. Many medicines that slow down intestinal motility/peristalsis (diarrhea and nausea medicines) are verrrrrrrry mild opiates themselves.

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#5 of 9 Old 06-11-2010, 07:31 PM - Thread Starter
 
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Wonderful

I am actually on my 3rd dose today and I have never had to take 3 doses. Instead of being able to tolerate throwing up a few times like before, as soon as I feel my stomach churning, around the 8 hour mark, I need to take it.

I am little worried because I afraid I won't know when to taper down - I still feel sick while on it but I am trying to keep at the smallest dosage so it won't be as hard to wean myself off.

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#6 of 9 Old 06-11-2010, 07:39 PM
 
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I waited till well into the 2nd trimester and it was fine then. I think it is too soon for you.

DS1 2004 ~ DS2 2005 ~ DD1 2008 ~ DS3 2010 ~ DD2 due Dec. 2014
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#7 of 9 Old 06-11-2010, 07:46 PM - Thread Starter
 
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I waited till well into the 2nd trimester and it was fine then. I think it is too soon for you.
Thanks - last time I stopped at 26 weeks. The problem is the amount of pills I get (12 pill to last 2 weeks??) I am on my last refill and I don't know how this insurance is going to be with approving it. Last time it was a big fight after the first trimester. I guess I will just relax and keep taking when needed. I really wanted to not have to take it as long this time, but wishful thinking I guess.

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#8 of 9 Old 06-12-2010, 08:51 AM
 
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This pregnancy is the first one that the sickness has lingered the longest so I've needed the zofran longer.In the begining I needed the maximum dose but have found that as I get farther the less I'm needing.I am not needing it right at hour five and I've dropped a couple of dosing times just because I don't feel the need.I did think I was fine and the Dr kinda forced me to go off and even though it was a taper I ended up in L and D last week after 4 days of hell.Not good.
All of the meds work best if you are well hydrated so make sure you are getting fluids in.I didn't realize that and my Drs were/are unobservant and it also was a trip to the hospital.Good Luck and hopefully you'll well soon.

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#9 of 9 Old 04-27-2013, 12:29 PM
 
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I wondered about whether Zofran (generic name, Ondansetron) was habit-forming, and this was the first Google.Com entry.

 

I have to admit I am a guy, so not entirely sure what you ladies are experiencing. My doctor prescribed it since I was vomited (sorry to be gross!) either at time of taking a handful of pills or inexplicably. She told me Zofran is usually prescribed for cancer patients undergoing "chemotherapy", so I realized it was strong.

 

I have been on two types: CVS has dissolvable peppermint-tasting Ondansetron and Kroger Pharmacy had disssolvable strawberry-tasting. I am pretty sure that has played some role in my use of Zofran. It usually takes about 15 minutes for effectiveness, for me.

 

When I was last on a cruise, I remember "popping a pill" of it --"just in case." Like an earlier subscriber mentioned, she'd take twice the dose prescribed. Mine come in blister packs, two pills side by side, so I'd pop two also.

 

I was able to get away from Ondansetron for a while, but like most "helpful meds" I have been prescribed (such as Adderall [amphetamine salts, for Attention Deficit Disorder]) and Klonopin [generic name, clonazepam] for anxiety), I always request Ondansetron to be refilled --whether needed or not. With these three, I am like that. Adderall is a "controlled substance" here in HOUTX (Houston, TX, USA) where I live, not sure in other places, so a special prescription pad has to be used by my doctor --it cannot be automatically refilled by CVS.

 

I appreciate that each of you have shared your experience. I hope that I can "remain clean" of Ondansetron. I have an "addictive personality" coming from alcoholism on both sides of my family. My sister, whom I love more dearly than you can imagine, cannot handle alcohol. She gets very emotional and has "blackouts." We're Iro-American (for distant Irish heritage) on my father's side and there is Cherokee Amerindian on Mama's side.

 

Sincerely,

   Matthew Tobin

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