You should definitely PRE-wash your hemp and unbleached cotton separately from Pockets/AIOs or PUL covers. They need to be washed on HOT until all the natural oils are removed from the fibers. The oils need to be removed to make them absorbant. If you wash them with pockets/AIOs/Covers, there is a risk that the oils will transfer onto the other diapers and cause them to wick/leak/repel moisture. You'll know the hemp/Unbleached cotton is "primed" and ready to wash with the other stuff when you can squirt some water onto it (use a nasal aspirator or peribottle to simulate a "pee") and it gets absorbed. If it pools, keep pre-washing. If it soaks in, you're good to go with washing everything together. Depending on the hemp/cotton and the washing conditions, it can take anywhere from 3+ washes to achieve the "primed" status.
Hope that helps.