i'd be glad to give you my experience on letrozole! when we started ttc #1, i was 36. the clinic gave me literature to read and despite having no fertility issues - fsh, estradiol and lh all within range - they strongly suggested i use letrozole from the get-go. dp and i discussed it and since we had given ourselves 6 tries for me to get pregnant before switching to dp we decided to go ahead.
the first cycle i took 2.5mg cd3-7. at first it looked like i would have 3 follicles but in the end i just got one 19mm on cd15. bfn that cycle.
then we had my prolactin retested and i took a break to get that back to normal using dostinex.
the second cycle i took 5mg cd3-7 and also had a 150iu shot of follistim on cd8 (however, on talking with the re we're using now for dp she said one shot of follistim makes no sense AT ALL). i ended up with 4 follicles, 3 of which definitely ruptured. bfp that cycle which resulted in our wonderful son.
dp is on her second cycle using letrozole 5mg. first cycle was with the clinic that got me pregnant. she took it cd2-6 and also had a 150iu shot of follistim, her's was on cd7. she ended up with 2 follicles which both ruptured. bfn that cycle but she had extenuating circumstances - undiagnosed pcos, a 9mm polyp and tsh in the hyperthyroid range - any of which could have caused the bfn!!
we then switched to using an re. for her second cycle we are on cd7 and her last dose is tonight. we have a follicle check set for cd13.
dp and i had no major side effects of using letrozole. no headaches, no hot flashes, no nausea, no mood swings.