I have had 4 births and 4xd ppd. After the 3rd i took zoloft--worked great, kicked in right away. had to stop when i got pregnant again because i threw it up every time in tried to take it. started it again the day my daughter was born. 25mg. i had taken 50 before. it has been one week. i am so depressed and freaking out when my 3 boys are home. i can't stop crying. tell me it will kick in.......any experience with this?