I took Zoloft quite a few years ago when I was clinically depressed and suicidal, and I can honestly say it made it worse for me. I was feeling so out of control already that when my body started shaking and wouldn't stop no matter what I did, it made me feel like I had lost control of everything. I guess I felt at that time that this was the last thing I needed to do, I couldn't concentrate, on top of already having horrible concentration, I felt wired and anxious, and couldn't keep a thought still for a moment. I remember at one point just trying to hold my body still from shaking, and I just cracked. It was too much. I did give it some time, I can't remember how long now, but the side effects did not wane. It just got worse. So I stopped taking them. I tried Paxil as well, side effects also, not as bad, but I still reacted pretty violently.
Have you tried seeing a naturopath? Have you tried St. John's Wort? I know this has helped many people.
Depression is a horrible thing to experience, and I can understand wanting to try anything that might make you feel better. Just be aware, which you seem to be, that these are powerful drugs and they do alter other chemicals in your body as well. But, they work marvelously for some, so you have to do what feels right to you, and listen to your gut, which is hard to do when you're depressed I know, but if you aren't comfortable with the idea of putting a drug in your body to help treat your depression, perhaps looking into alternatives might be a good place to try? I felt the same way, it made me very uncomfortable, and with good reason.
If you ever need some suggestions or assistance with this don't hesitate to pm me.