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|Doing research for you, Jess (I'll keep adding to this post as I find links):
http://www.raysahelian.com/leukotriene.html Says fish oil is a leukotrine inhibitor, and herbs such as boswellia, pygeum, butterbur. That last one is interesting, DH tried that for migraines in a form sold as petadolex. Boswellia is a Ayurvedic plant.
http://www.itmonline.org/arts/lox.htm This one, down towards the bottom, says decrease dietary intake of PUFAs (polyunsaturated fatty acids), in particular, more omega 3s, less omega 6s. Olive oil has high oleanolic acid, also good. There is a nice table down the page of omega 3 and 6s in foods, and then of fish with high omega 3 content (I seem to remember some fish had never tested positive for you, not sure how that matches up with this list). This sounds more like a long term approach than a fast one though.
Tables 5 & 6, in this same document, have a list of natural substances that can inhibit important enzymes in producing leukotrienes. Looks like a pretty comprehensive list. Ideally you'd want to try at least one substance from each table (they block two different enzymes). There's one substance called ursolic acid (a component of some Chinese herbs), that is in both tables, and one of the stronger inhibitors. It comes in apples, sage, cranberries, oregano, basil, peppermint - any of those safe? Oh, and tea catechins are good, can you drink tea?
|CS - *I* have used Singulair. I started taking it back in ...2001, I think, when it was quite a new drug on the market. I was having asthma attacks and getting wheezy in the middle of the night, just from getting up at 2am to pee. I had asthma as a child, but it had largely gone away in my 20s, and then in my early 30s, it was back again. I finally went to my family doc and started Singulair. To my knowledge, I did not experience side effects. It did help tremendously with my wheezing. I finally went off it a few years later, tapering down to 1 dose a day (I think the typical dose was twice a day), then less. Finally stopped taking it...2005 maybe? A combination of (1) figuring out I was probably allergic to cats; and (2) acupuncture, perhaps, let me stop taking it.
I will be reading up on Singulair, as our family doctor mentions it each time DS is in for wheezing. We are trying to eliminate his triggers, and we're managing it quite well with a humidifier. But, we may decide to do the Singulair. DH doesn't like giving drugs, but he is much, much more in line with Western medicine, doesn't agree with supplements or anything alternative, and, although he cooks (primarily whole foods), he isn't into figuring nutrition out with me. So, if DS's wheezing isn't controlled well in the future, we may very well find ourselves trying Singulair for him within a year or so.
And interesting that mamafish says fish oil is a leukotrine inhibitor, as I had an intuition that DS should get more fish oil.
My daughter is taking Singulair, a leukotriene inhibitor for eosinophilic esophagitis. EE is caused by non-IgE allergies and sensitivities, most of which are usually food-related, though there are environmental allergies at play as well.
Taking huge amounts of GLA will boost your natural leukotriene inhibitors, as will taking flaxseed oil and fish oil. The GLA is key, though, as well as reducing consumption of junk fats.
It's not like taking Singulair means DD can eat the foods to which she has an allergy. Not at all. It has dampened her worst EE symptoms, specifically episodes of choking sensations. EE isn't like regular food allergies or even sensitivities, the patient may have food "triggers" that are extremely difficult to diagnose and environmental allergies make it worse as well. We don't know why the Singulair helps.
Singulair apparently is notorious for causing psychological problems with kids. My DD was on a high dose (10 mg./day, twice the normal pediatric dosage) and having attacks of rage, anxiety and depression. It was so bad that we had to lower her to the regular pediatric dosage of 5 mg./day.
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