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And to add on to mammo2sammo's post, I'd look especially at methylation and sulfation detox pathways. Meaning, are you getting enough nutrients? How are you on folate (not folic acid), B12, magnesium, B6, and molybdenum (found primarily in legumes and other nitrogen fixing plants)? Do beets turn your pee pink? If so, you may not have enough stomach acid, and so malabsorption, especially of B12 is likely.
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