Post #20 from Healing the Gut Tribe Cheat Sheet on Probiotics and Infants
With respect to infants and gut flora:
Bifidobacteria comprises 91% of microflora of BF infants and 75% of FF infants. (Harmsen et al, 2000)http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
The bifidus dominance and exclusive BF'ing seals up the gut mucosal lining. This is extremely important for the immune system to start to develop the ability to recognize "self" vs. "non-self". The gut flora is 70% of the innate immune system primary defenses (basis of the GALT, MALT and BALT immune systems).
There is also a lot of evidence that colicky behavior, and sleeping and stool problems, with infants are a direct result of the imbalance of gut flora. So bifidus supplementation might be a good first step for correction or prevention of behavioral and immune system diseases.
Edit: B. Infantis is the correct human strain that is preferred. Natren Life Start or Solaray BabyLife or Pharmax Neonate. The second is dairy free if you know for sure your babe is allergic to dairy. Interestingly, Elizabeth Lipski PhD author of Digestive Wellness for Children recommends probiotics made from dairy if they are well tolerated by the child as helpful in aiding the body to digest dairy. She also states that she has seen B. Infantis correct colic in newborns within days and uses it in her clinical practice. Also indicated for cradle cap and eczema.
Intestinal flora in the neonate: impact on morbidity and therapeutic perspectiveshttp://www.ncbi.nlm.nih.gov/entrez/q...t_uids=9759211
Just One Bottlehttp://www.massbfc.org/formula/bottle.html
The Case for the Virgin Guthttp://breastfeed.com/resources/articles/virgingut.htm
Developmental microbial ecology of the neonatal gastrointestinal tracthttp://www.ajcn.org/cgi/content/full/69/5/1035S
Beneficial Baby Bacteria: Their Key Benefits, Functions, & Selectionhttp://www.natren.com/pages/natashart3.asp
Your Baby's Best Advantage – Probioticshttp://www.natren.com/pages/baby.html
Further studies found differences in the gut flora of infants who are likely to develop allergy. When compared with healthy infants, babies who developed allergy symptoms were less often colonized with bifidobacteria. These results could indicate a role for the intestinal microflora in the development of and protection from allergy, especially in developed countries, where antibiotic therapy and sterile C-section deliveries are far more common.
Childhood eczema is almost entirely caused by food allergies, noted Dr. McCann. “We also know that one allergy can predispose to another. In other words, if food allergies and eczema can be prevented, then so also can asthma.” He adds, “In future years, every newborn baby will receive with her first feeding, a goodly gulp of a friendly bacterial mix. Meanwhile, we are stuck with treating after the fact, rather than prevention.”
Of the many factors suggested to explain the worldwide increase in asthma, "We have found only one primary prevention, the maintenance of a normal bowel flora," reported pediatric allergy specialist Dr. Bengt Bjorksten, in an address to the American Academy of Allergy, Asthma and Immunology Studies, Stockholm, Sweden. Studies from Europe show that newborns with abnormal flora have many more times the prevalence of allergic disease. If the baby does not have a good GI barrier, it sets the stage for increased allergic disease.
Effects of intestinal microflora and the environment on the development of asthma and allergy.
Centre for Allergy Research and Department of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden. firstname.lastname@example.org
Recent studies have shown differences in the composition of the microflora between healthy and allergic infants in countries with a high and low prevalence of allergies and between healthy and allergic infants within such countries. These differences are apparent within the first week of life and thus precede clinical symptoms.
Evidence of probiotics in prevention of allergy and asthma.
Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden. email@example.com
Recent epidemiological studies and experimental research suggest that the microbial environment and exposure to microbial products in infancy modifies immune responses and enhances the development of tolerance to ubiquitous allergens. The intestinal microflora may play a particular role in this respect, as it is the major external driving force in the maturation of the immune system after birth and animal experiments have shown it to be a prerequisite for normal development of oral tolerance. The composition of the microflora differs between healthy and allergic infants and in countries with a high and low prevalence of allergies. These differences are apparent within the first week of life, or even in the maternal vaginal flora during pregnancy and thus precede clinical symptoms.
Two very common things given to babes or BF'ing mamas that greatly effect the infant's ability to lay down and keep proper gut flora balance:
Also note: If you have yeast/thrush you are passing this on to your babe's flora. There is indication that yeast does indeed change the immune systems reaction to foods:
Animal Studies Show Gut Flora/Antibiotics Effect Oral Tolerance
Antibiotic administration early in life impairs specific humoral responses to an oral antigen and increases intestinal mast cell numbers and mediator concentrations.http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract
The reconstitution of intestinal flora of GF mice with Bifidobacterium infantis, one of the predominant bacteria in the intestinal flora, restored the susceptibility of these Th2 responses to oral tolerance induction; however, this was only effective when such reconstitution was performed in neonates, but not in mice at an older age.
Antibiotics and Infant Gut Flora from MThttp://www.mothering.com/discussions...2&postcount=24