My son is oddly cooperative when it comes to things like this so it might not work for you but I had him pick out a sticker I kept with the drops (cats, dogs, flowers, etc) and he would lay on the floor, I sat, we talked about the sticker (Does that dog meow? That dog wants to kiss your face!) and I put the drops in as best as I could - open eyed, closed eyed, whatever. Sometimes I'd give a second sticker afterward. Tried to keep it as light and fun as possible.
Boys: 12/94, 1/99, 11/03, 6/11. Girls: 11/06, 10/09, 12/12