My best thrift store purchase? A month or so ago, I bought a gorgeous chocolate brown leather sofa for $375 (it was marked $500 but a senior got the discount for me). It is in perfect shape. It was donated from someone who lives in a high rise that tends to house big wigs from Proctor and Gamble and professional atheletes. After a 40 minute Internet search, I found the exact couch brand new for $1695. WooHOO!!
I also scored a Patagonia Fleece for my DD for $1.50 and three pairs of Ralph Lauren khakis for $6. I got a wool blend Saks Fifth Avenue cardigan for me for $3.99. All of that was at the St. Vincent de Paul. I find Goodwill to be too expensive. They mark things up terribly. We also have a chain here in Cincinnati called Village Discount Outlet. They have $0.50 Mondays. I love it!!