I think its a great idea. But keep in mind what you're donating. I have heard from some volunteers sorting out things that people will donate just about anything. 1 in every 3 things had to be discarded because it was so worn out or badly stained etc. So donate new or gently used clothes. If you have clothes that your kids beat up, think twice anyway about donating. But out grown things that were not used as much are fine.
Also consider buying a pack of onesies and washing them to donate. Encourage others to do the same. Some things I have heard that need to be brought down to the area are: t-shirts, shorts, sun block, flip flops, ready to eat meals (pop tarts, power bar type things), gift cards to various groceries, wal mart, gas etc, and of course all baby items.
Consider donating a car seat, stroller, baby carrier or sling to local drives for people coming in.
Please also, do not neglect the normal charities you also give to. They are all going to suffer since everyone is giving to the Katrina disastar right now.
"The true joy of life is the trip. The station is only a dream. It constantly out distances us."