I read a book recently that said one of the important ways to keep things organized is to label every space. Like having a "shirt" and "pants" drawer in your dresser, to give a small scale example.
Naturally, the worst disaster area in my house has been the "spare room". It began life as the video room, and when the tv was moved it lost that identity.
Dh had a fabulous idea, it's going to be a study! We're going to set it up with a computer just loaded with software suitable for school work and a desk and a wall of bookshelves. I've been having fun mentally planning what we'll do in there which is a complete change from the despair I had felt when I looked around that room.
Unfortunately, we won't really start in on that room until we finish replacing the carpet in the kitchen with tile.