My sister had diarrhea so bad on Zoloft, she had to switch to Lexapro.
I have some nausea, but I've found I need to eat both before and after I take it. What I did yesterday was I ate my lunch, took the pill, then had my dessert (cookies and milk). This worked out perfectly.
Last Friday I took it on an empty stomach, then I took a nap (no food for 1+ hrs). When I got up and started moving around I was paralyzed with nausea. It took more than 2 hours to get back into the swing of things, and I still felt bad until bedtime. I was having to force myslef to eat because I knew it was the only thing that would help.
I talked to my sister at length about the side effects (both the sexual and being so sleepy all the time), and she said that she had the same problem on Lexapro, but her body eventually figured it out. I told her I was already ready to quit, but she said I need to given it at least one more week at my current dose (50mg) - that'll be the 2.5 week mark. Then if I'm still over-tired, I could cut the pill in half and see if 25mg is a better does for me. Of course, she admitted this is technically "self-medicating," but as long as I'm not doing anything crazy like uppping myself to 200mg over-night I won't hurt myself by tweaking my dose on my own . . .