After a while the box will get a build up of hard , scaley urine, Vinegar works great, straight vinegar soaking in a box for about 20 minutes and all you will have to do is wipe it away. Lysol wipes inbetween deep cleanings should be fine. A good litter to use is horse stall pellets, you can get them at a tractor supply store they are called Equine pine, or Equine fresh. You can get a 40lb bag for under 8.00, a great value, i use it in my rabbits boxes.
You could also look up something called C&C Cages, they are geared towards guinea pigs but rabbit people all over use them. I belong to a rabbit message board and most of the people there use C&C Cages, sometimes called NIC cages. Another thing to help with the poops is a mesh screen that you can put on top of the litter and just pick up and dump, the pee will go down and into the litter. I put the hay right ontop of the litter too.