The rash after Chicken pox vaccine.. - Mothering Forums

Forum Jump: 
 
Thread Tools
#1 of 6 Old 04-12-2007, 03:36 PM - Thread Starter
 
marlne's Avatar
 
Join Date: Mar 2006
Posts: 380
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 0 Post(s)
If a child gets a rash after receiving the chicken pox vaccine, are they contagious? The rash is similar to the chicken pox.
A friend vaccinated her little one with the chicken pox vaccine and now she's got the rash. The doctor says she is fine to go back to daycare like that but she was worried about the child being contagious.
marlne is offline  
Sponsored Links
Advertisement
 
#2 of 6 Old 04-12-2007, 03:47 PM
 
mamakay's Avatar
 
Join Date: Apr 2005
Location: in la la land, or so they say...
Posts: 8,332
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 13 Post(s)
Yes. The virus present in the post-vaccine rash is basically wild chickenpox.
mamakay is offline  
#3 of 6 Old 04-12-2007, 03:59 PM - Thread Starter
 
marlne's Avatar
 
Join Date: Mar 2006
Posts: 380
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 0 Post(s)
So the baby basically does have the chicken pox if she presents that rash post vaccination?
I'll let her know.
So if a doctor says the child is not contagious, does this follow suit with some doctors not knowing what is in the vaccines as well?lol

The doctor told her that because the child has no fever, she is not contagious but if she presents a fever, then she will be contagious. How confusing?

I just got more information from her.. She said the child had the vaccine mar. 21st and presented the rash april 10th. That would make it different, correct?
marlne is offline  
#4 of 6 Old 04-12-2007, 04:31 PM
 
mamakay's Avatar
 
Join Date: Apr 2005
Location: in la la land, or so they say...
Posts: 8,332
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 13 Post(s)
Quote:
So the baby basically does have the chicken pox if she presents that rash post vaccination?
I'll let her know.
So if a doctor says the child is not contagious, does this follow suit with some doctors not knowing what is in the vaccines as well?lol
Yep. The chickenpox vax has a whole spectrum of viruses in there. Some are attenuated, and some aren't, and the virus isolated from the post-vax rash is "unattenuated" (wild). This is pretty recent (as in, just discovered a year or 2 ago) research, though. So most docs still don't know that.

Quote:
The doctor told her that because the child has no fever, she is not contagious but if she presents a fever, then she will be contagious. How confusing?
I'm not absolutely sure, but I'm fairly confident the doc is just making that up.

Quote:
I just got more information from her.. She said the child had the vaccine mar. 21st and presented the rash april 10th. That would make it different, correct?
No, I don't think that would change anything. There's a lot of variation on how long different people "incubate" chickenpox.
mamakay is offline  
#5 of 6 Old 04-12-2007, 04:36 PM - Thread Starter
 
marlne's Avatar
 
Join Date: Mar 2006
Posts: 380
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 0 Post(s)
You are such amazing help! Thank you so much for taking the time, I really appreciate it!
It should be interesting now if something comes of this, since the momma did take her baby to the childcare.
She also just mentioned a child in her classroom presenting the chicken pox the other day as well. (the mom teaches and this is in her class of students)


Thanks again!
marlne is offline  
#6 of 6 Old 04-12-2007, 05:18 PM
 
mamakay's Avatar
 
Join Date: Apr 2005
Location: in la la land, or so they say...
Posts: 8,332
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 13 Post(s)
Yer welcome.

Here's some science in case anyone's interested...

http://www.pubmedcentral.nih.gov/art...5228&tools=bot

Quote:
We demonstrated here that an in vivo-selected virus, V-Oka-zoster, isolated from a vaccinated zoster patient has wild-type ORF 10 and that it emerged from a vaccine preparation containing both vaccine and wild-type gene 10 variants (Table 2). The isolated vaccine variant also displayed the wild-type SNPs for 9A (a structural protein), 21 (capsid assembly protein), 52 (DNA helicase/primase complex, associated protein), and 55 (probable helicase, required for viral replication), any of which might also contribute to differences in pathogenicity.
Quote:
These findings confirm that both GlaxoSmithKline and Biken varicella vaccines are mixtures of several variants of attenuated VZV, some of which are likely to vary with respect to degree of attenuation. Detailed evaluation of every identified vaccine-specific SNP and their relative proportion in vaccine preparations is outside the range of this report and will require careful investigation. Importantly, V-Oka-zoster represents a single vaccine-related VZV strain, a variant that contained six wild-type (P-Oka) bases at identified vaccine SNPs and otherwise carried only vaccine-associated SNPs. None of these six polymorphisms reliably distinguish VZV Oka vaccine from wild-type VZV, since they represent SNPs that are variably expressed in the V-Oka-GSK mixture.

http://www.journals.uchicago.edu/cgi...546263147Guest

Quote:
Vaccination against chickenpox causes a varicella-like rash in up to 5% of healthy children and 50% of children with leukemia. The vaccine may establish latency and reactivate to cause herpes zoster, albeit more rarely than wild-type virus. All vaccine preparations are composed of a mixture of varicella-zoster virus strains that show genotypic variation at several loci. We have shown, by DNA sequencing of 40 polymorphic loci, that viruses sampled from vesicles in varicella-like and herpes zoster rashes are single clones. This finding suggests that, between the time of inoculation of the vaccine and development of rash, selection of single strains occurs. The results have general implications for the pathogenesis of varicella-zoster virus.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=17182747

Quote:
Indeed, most of the novel mutations distinguishing the Oka vaccine from the more virulent parental virus have not actually become fixed. Because the parental alleles are still present, the vaccine is polymorphic at >30 loci and therefore contains a mixture of related viruses. The inoculation of >40 million patients has consequently created a highly replicated evolutionary experiment that we have used to assess the competitive ability of these different viral genotypes in a human host. Using virus recovered from rash vesicles, we show that two vaccine mutations, causing amino acid substitutions in the major transactivating protein IE62, are outcompeted by the ancestral alleles.
mamakay is offline  
Reply

User Tag List

Thread Tools
Show Printable Version Show Printable Version
Email this Page Email this Page


Forum Jump: 

Posting Rules  
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are Off