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I really like looking at seroepidemiology to figure out what the chances are for various stuff.
By middle age, one out of three of us has been infected with hepA. So, between me, angela, and carrie...one of us has probably had it and never knew what it was.
Whoever it was probably got "sick" to some extent, but not enough to get a diagnosis.
By the time you're a lot older (I think over 60?) it's 2/3rds who've been infected. And again, I don't know too many folks who know when they had HepA. I guess it's one of those "that time my guts were weird for 3 weeks" type things.
|The prevalence of antibody to hepatitis A virus in the general US population was 38.2%, based upon testing of 9516 participants from the second National Health and Nutrition Examination Survey conducted from 1976 to 1980. Prevalence increased steadily with age, ranging from 11% in persons < 5 years of age to 74% in persons > or = 50 years old.|
|One in three does not mean that one of you three could have had it and not known it.|
|74% in persons > or = 50 years old.|
Yes, it does.
Do you really think 3 out of 4 people over the age of 50 remember when they had HepA?
|they do not mean that you can take three people and find that one of them has it. They mean on average, one in three out of the populace as a whole.|
|In addition, relapse is possible with hepatitis A. This usually occurs within three months of the initial onset of symptoms. Although relapse is more common in children, it does occur with some regularity in adults.
On average, the time to full recovery takes about 2 months, but 10-15 percent of persons have a prolonged or relapsing course lasting up to six months (Gilkson, et al., 1992; Willner, et al., 1998).
|The incubation period for hepatitis A averages 28 days (range 15-50 days). Hepatitis A typically has an abrupt onset of symptoms that can include fever, malaise, anorexia, nausea, abdominal discomfort, dark urine, and jaundice. The likelihood of having symptoms with HAV infection is related to the infected person’s age. In children younger than 6 years old, most (70%) infections are asymptomatic; if illness does occur, its duration is usually less than 2 months. No chronic or long-term infection is associated with hepatitis A, but 10% of infected persons will have prolonged or relapsing symptoms over a 6- to 9-month period. The overall case-fatality rate among cases reported to CDC is 0.3%; however, the rate is 1.8% among adults older than 50 years of age (1).|
|Prolonged forms of HAV infection are atypical forms of diseases which occur in up to 24% cases.|
|Seven (11.9%) of the 59 patients in our study
had a relapse of acute hepatitis A,
One in three does not mean that one of you three could have had it and not known it. You all could never have had it. Yes you could have had a mild case of it. Or you can get a really bad case of it, like me.
I have had it and it sucked big time and my liver was affected and I had jaundice. I was sick for weeks.
|I can never donate an organ or blood, ever.|
I'd also like to know more about all these lines saying "average recovery is two weeks to two months" or "most are recovered by two months"
that seems like a LONG time....can there be symptoms for two months?? or does that just mean they showed no immune system signs of the disease aftrer two months?
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