So why have we not heard any mention of this?
"The inactivated DTP vaccine worryingly has been associated with increased mortality from other infectious diseases. Both positive and negative effects are strongest for girls."
Please read the whole abstract, as there are several interesting findings presented.
Off to try and track down the original study . . .
Rrrrachael, those are really good questions.
I think it's great to investigate ways to prevent death from illnesses, but there are so many confounding factors, incorrect assumptions, and limitations in the way these studies were done. And it really bothers me that deaths of female children were written off in 1995 as being unrelated to the vaccine, when now we know that there ARE factors that affect response to both vaccine and illness by gender.
I am between institutional logins at the moment, maybe someone who does have one can hook us up with some summaries or something.
Most of these seem to be dealing with high mortality countries. I haven't found anything to say whether or not the results apply to somewhere like the us.
"In the study from Benin West Africa (18), although the estimated increase in mortality following one dose of DTP and one dose of oral poliovirus vaccine (OPV) was elevated compared with unvaccinated children (relative risk = 2.2), this increase was not statistically significant. The risk estimate decreased with increasing numbers of DTP doses from 2.2 at one dose of DTP to 0.7 at four doses. With respect to BCG vaccine, the estimate for mortality reduction in vaccinated vs unvaccinated children was 0.38."
Lots more good stuff here. Glad this study isn't just being ignored!