Join Date: Jun 2004
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We're not inclined to get DTaP for our infant, DS2. But, I was wondering if there is any information out there whether the first dose (the one the CDC recommends getting at two months) is meant to confer any amount of immunity. We're going to the two-month appointment in a few weeks, and I can imagine being told that even that first dose will do "something". When looking into this five years ago with DS1, I thought I saw that it takes three doses to have any immunity--and, by that point, the baby is out of the danger range (and wasn't protected at all by the first three doses until all three were received). I looked at the pink book, and either the 2009 edits took that part out or I read this somewhere else.
|There isn’t much data on the efficacy and protection from one or two doses of DTaP. Pertussis vaccine trials are difficult to do. Virtually everyone who has looked at this issue uses 3 doses as the benchmark. We know that with 3 doses efficacy is 80%-85%. We know that two doses are better than one, and one dose is better than none. But I don’t know of any data that would give us a feeling of how well one or two doses would protect against pertussis. (2/20/03)|