discussion on how efficacy and effectiveness rates are determined - Mothering Forums

Forum Jump: 
 
Thread Tools
#1 of 5 Old 06-17-2012, 03:24 PM - Thread Starter
 
purslaine's Avatar
 
Join Date: Feb 2006
Location: Canada
Posts: 6,937
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 0 Post(s)

https://www.hidionline.com/hidi/Documents/Vaccine_Epidemiology.pdf

 

I thought this was a really interesting discussion on how efficacy and effectiveness rates are determined.

purslaine is offline  
#2 of 5 Old 06-24-2012, 06:55 AM
Administrator
 
cynthia mosher's Avatar
 
Join Date: Aug 1999
Location: Arabia!
Posts: 38,849
Mentioned: 14 Post(s)
Tagged: 1 Thread(s)
Quoted: 98 Post(s)

Thanks for sharing. thumb.gif


cynthia mosher is online now  
#3 of 5 Old 06-24-2012, 07:15 AM
 
Taximom5's Avatar
 
Join Date: Jan 2012
Posts: 3,135
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 36 Post(s)

That's fascinating--because it's TOTALLY different from what most people believe.

 

Most people think that a vaccine that is 58% effective will prevent the disease in 58% of the people who receive the vaccine.

 

In reality, 58% fewer vaccinated people will get the disease compared with unvaccinated people--and in many cases, like influenza, unvaccinated people who wash their hands, get proper nutrition and rest, etc., are unlikely to get the disease in the first place.

 

Great article--thanks for posting!

Taximom5 is online now  
#4 of 5 Old 06-24-2012, 07:18 AM - Thread Starter
 
purslaine's Avatar
 
Join Date: Feb 2006
Location: Canada
Posts: 6,937
Mentioned: 0 Post(s)
Tagged: 0 Thread(s)
Quoted: 0 Post(s)
Quote:
Originally Posted by Taximom5 View Post

That's fascinating--because it's TOTALLY different from what most people believe.

 

Most people think that a vaccine that is 58% effective will prevent the disease in 58% of the people who receive the vaccine.

 

 

Great article--thanks for posting!

 

That is what I believed until about a week ago, lol.

 

The article was a real eye opener.

purslaine is offline  
#5 of 5 Old 06-25-2012, 02:20 AM
 
prosciencemum's Avatar
 
Join Date: Jan 2012
Posts: 1,748
Mentioned: 1 Post(s)
Tagged: 0 Thread(s)
Quoted: 99 Post(s)

That is a good thing to share. It's important to check we understand the statistics. 

 

Of course if you think about it effectiveness has to be something you can measure, and a VPD can only be caught if you're exposed to the bacteria/virus which causes it. So it would be impossible to measure which fraction of people vaccinated are protected from the disease - the only way to do that would be to deliberately expose them to the diseases after they were vaccinated. And that kind of testing is clearly unethical. 

 

So all they can do is take a sample of vaccinated and unvaccinated people who live in a similar environment (I assume they do their best to control for things like socio-economic group, geographic location etc) and see how the rates of the disease differ in the vaccinated and unvaccinated populations.

 

Ultimately if a vaccination can become widespread enough that the disease dies off (like it did for small pox) and then the vaccination is no longer needed that would be the best results. I realise that is probably a pipe dream for many of the diseases today (which if I understand the argument seem to mutate more than small pox did), but it would still be fantastic. :)  


Mother of two living in UK. Daughter (2007) born in USA, son (2010) born here. I'm pro natural birth, midwife care, breastfeeding, co-sleeping, baby wearing and a keen advocate of cloth diapering. I'm a full time working research scientist (physical sciences) and I'm pro-vaccine.

prosciencemum is online now  
Reply

Quick Reply
Message:
Drag and Drop File Upload
Drag files here to attach!
Upload Progress: 0
Options

Register Now

In order to be able to post messages on the Mothering Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
If you do not want to register, fill this field only and the name will be used as user name for your post.
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



User Tag List

Thread Tools
Show Printable Version Show Printable Version
Email this Page Email this Page


Forum Jump: 

Posting Rules  
You may post new threads
You may post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are Off