Originally Posted by applejuice
If the measles vaccine is so darn wonderful and free of side effects, why is SSPE still a problem at all?
Why are doctors NOW, after 50 yrs, learning that SSPE really is still a health problem, despite the vaccine and SSPE is more common that previously thought? What is SSPE being confused with in the diagnosis process?
Many doctors do not know how to properly diagnose SSPE since they wrongly assume that the vaccine does the job.
Is there an SSPE vaccine in the works?
From the OP link:
The team started to look at possible SSPE cases after the German cases were reported. They found 16 people in California alone killed by SSPE - all diagnosed by autopsy after they died.
Did these people just expire without any symptoms? If doctors aren't diagnosing SSPE in people with a measles history whilst the patient is alive, why would we think they would diagnose SSPE in previously vaccinated people?
Patient: "Doc, I'm experiencing (insert SSPE symptoms here
Doc: "Have you ever had the measles?"
Patient: "No. I was vaccinated with the measles vaccine".
Doc: "Well can't be SSPE then".
Incidence of subacute sclerosing panencephalitis following measles and measles vaccination in Japan.
Okuno Y1, Nakao T, Ishida N, Konno T, Mizutani H, Fukuyama Y, Sato T, Isomura S, Ueda S, Kitamura I, et al.
The Japanese Committee for the National Registry of Subacute Sclerosing Panencephalitis (SSPE) confirmed that 215 cases of SSPE occurred in the 20 years from 1966 to 1985, as discovered in the 10-year surveillance from April 1976 through March 1986. The annual incidence in recent years has been between 10 and 23 cases. Among cases with a certain history of measles illness or measles vaccination, 184 (90.2%) had a history of measles illness without receiving measles vaccine. There were 11 probable measles vaccine-associated cases (5.4%), three (1.5%) being vaccinated with a combined use of killed and live vaccine and eight (3.9%) with further attenuated live vaccine. There were nine cases (4.4%) without a history of either measles illness or measles vaccination.
So probable measles vaccine associated cases in Japan. And nine cases of no history of either measles illness or vaccination. What else causes/is associated with SSPE then?
Here's another case of SSPE following vaccination:
Measles, mumps, rubella vaccine induced subacute sclerosing panencephalitis.
Belgamwar RB1, Prasad S, Appaya P.
The risk of SSPE after measles vaccination has been estimated at 0.7/million doses. This paper reports the case of a 15-year-old girl from India who developed SSPE presumably as a result of a delayed effect of measles, mumps, and rubella (MMR) vaccine. She presented with a 2-month history of behavioral disturbances, a deterioration in school performance, forgetfulness, silly smiling, handwriting changes, social withdrawal, and ataxia. The girl had received MMR vaccine at 9 months of age and had no past history of measles. Her measles antibody titre was 1:625 in both serum and cerebrospinal fluid.