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|Pertussis is considered an endemic disease, characterized by an epidemic every 2–5 years. This rate of exacerbations has not changed, even after the introduction of mass vaccination – a fact that indicates the efficacy of the vaccine in preventing the disease but not the transmission of the causative agent (B. pertussis) within the population|
|Serologic studies suggest that the rate of B pertussis infection in adolescents and adults is 2.0% per year. The rate of cough illnesses (pertussis) caused by B pertussis infection in adolescents and adults is between 370 and 1500 per 100 000 population. These data suggest that there are between 800 000 and 3.3 million cases per year in the United States.|
|This definition required 21 days of paroxysmal cough plus laboratory confirmation of pertussis in the subject or household contact. There are 2 problems with this definition. The first is that a substantial number of B pertussis infections in unvaccinated children are mild and would not meet the case definition. The second is that all pertussis vaccines tend to modify duration and severity of disease rather than completely preventing illness.18,2326-29,35,36,40 Therefore, the WHO definition has made all vaccines look better than they are and it has tended to obscure differences between vaccines|
|Since the neurologic picture is not specific for pertussis vaccination, its temporal relationship to the vaccination is the critical variable for determining causation. Although the majority of seizures following pertussis vaccination are associated with fever, it was the consensus of the neurologists attending the workshop, that these do not represent febrile convulsions, but are non-benign convulsions. The incidence of post-vaccine encephalopathy is difficult to ascertain|
|In rare cases (about 100 children out of 10,000 shots given, or about 1%) children have moderate reactions such as prolonged crying, fever of 105 degrees or higher, seizure, or the child becoming limp, pale, and less alert.|
|After 67,000 doses, 153 serious adverse events (0.23%) were reported, 8 considered possibly related, and 5 related to vaccination, including 1 hypotonic-hyporesponsive episode.|
Now my point is, the pertussis vaccine is advocated to protect newborn infants from receiving pertussis, yet the vaccine does not stop transmission. 1% of those vaccinated have moderate adverse reactions and 0.23% have severe reactions.
An issue I find troubling is that since the vaccine lessens the severity of the cough, many people with whooping cough may not know they have it and thus may come into contact with infants and thus pass this on to the infant. The infants getting pertussis will be blamed on the unvaccinated as the issue when in reality it is more likely that an undiagnosed mild case carrier gives the disease to the infant.
DS 2006 DiaperFreeBaby March 2010, DD 2011
I totally understand this part, but why don't I hear about infants (not vaxed or not fully vaxed) getting pertussis all of the time? You'd think you would hear a lot more of that. Especially since it's worse for that age. Or are they, and it's just getting diagnosed as something else?
|so there's a chance it's pretty effective at reducing the symptoms enough to guarantee that most vaxed babies who catch it won't be diagnosed.|
|Mamakay, what do you think? Do you think the Pertussis vax doesn't prevent transmission?|
|Case definition has been particularly problematic in all of the recent DTaP vaccine efficacy trials. For uniform comparative purposes a case definition was suggested by a WHO expert committee.39 This definition required 21 days of paroxysmal cough plus laboratory confirmation of pertussis in the subject or household contact. There are 2 problems with this definition. The first is that a substantial number of B pertussis infections in unvaccinated children are mild and would not meet the case definition. The second is that all pertussis vaccines tend to modify duration and severity of disease rather than completely preventing illness.18,2326-29,35,36,40 Therefore, the WHO definition has made all vaccines look better than they are and it has tended to obscure differences between vaccines|
|In discussion, Dr Cherry pointed out that in Japan also the reported pertussis incidence in children under three months of age has not declined substantially with return to a high vaccination coverage.|
|“It is unknown whether immunizing adolescents and adults against pertussis will reduce the risk of transmission to infants.”|
Right, but no solid evidence or information from current studies. I just think that is really important for people to hear. That studies are old and evidence frequently anecdotal. Particularly for mom's no longer nursing or who can't. And even dosing mom and nursing, without evidence of how much C is being transmitted and used by the child, it's sort of a shot in the dark (no pun intended), don't you think?
Certainly none of this is concrete enough to call a definite treatment. Most illness respond to antibiotics. That is an example of a definite treatment in my book.
But you can't just put that out there without delving into WHY recent research and evidence isn't there about Vitamin C and it's role in health and healing. Care to venture to guess why it's not being looked into? Just saying the evidence is "old" is deceptive. Why do you need evidence on the amounts of Vitamin C? Do you know how it works? The dosage needed for each person is highly variable on the individual as well as their health status, but luckily, our bodies are pretty clear on telling us when we've reached a threshold level of Vitamin C. Just because "science" looked into it before but isn't currently looking at it doesn't mean that it's not a safe/effective treatment.
By the way, you wanna talk about old? Go look up the package insert of the MMR, and look at the dates of some of the studies that are cited on it. Then we can address the double standard.
|The whole-cell vaccine for
pertussis is protective only against clinical
disease, not against infection (15-17). Therefore,
even young, recently vaccinated children may
serve as reservoirs and potential transmitters of
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