I don't have a single job that takes me out of the house several days a week, so my experience may not apply, but I do WOHM and WAHM part-time while homeschooling and it's been working out well so far.
I have one teaching job that requires me to find childcare once a week during the day. The kids go to my sister and have a very active morning with her while I teach intermediate French (and sometimes Intro to Psych) to homeschooled teens at a local co-op. I have one tutoring job once a week in the evening where dh takes on solo duty while I go to their house for a few hours.
I run two part-time businesses out of my home that I often do with the kids or around their schedule. Sometimes I need to have meetings, go to trade shows or other events, etc., and dh takes the kids then, as well. If he can't, I arrange childcare with my sister or my parents. It definitely helps to have a local support system and family that I can trust close by. I'd be in a crunch otherwise.
The rest I do with the kids in tow -- I teach a couple classes for younger kids that mine also attend. They also have come to some meetings with me, on supply runs, etc. When they have activities where I don't need to participate with them, I bring work with me and sit on the side with that while I watch them. I consider the exposure to their mother running a small business to be part of their education, on several levels.
Philosophically, we generally unschool -- we provide exposure to different activities and experiences and pay attention to what they're interested in. This makes for a fairly busy activity schedule, but also a flexible one, and we try to work together to make sure everyone's getting what they need in balance with the rest of the family. Right now dd (5) has piano and drama classes once a week, ds (3) has occupational therapy twice a week, and they both have swimming and a day of homeschool co-op classes once a week. DH works a standard M-F 9-5, but he's trying out a schedule where he works at home twice a week, giving him a little more flexibility on his hours and the option of hanging with the kids while I do some work independently. Somehow it all comes together.