|Topic Review (Newest First)|
|09-19-2014 03:07 AM|
I am also recovering from adrenal fatigue. it is quite a complex process to heal your adrenals, because there a quite some factors that influence the adrenals. What i found out is that the adrenals are quite resilient, but like everything else they need to get a break to heal. Most important is to understand that there are root causes and other causes.
In my case mercury was the root cause, but gluten was definitely a cause in my lack of progress.
To support my adrenals i use a supplement called metarelax: Metarelax supplement, this calms me a bit down during the day and it helps me with my sleep during the night. Since i use it i have better sleep, with lots more deep sleep (sleep app). I also use some other supplements, vitamin C en E are quite important.
Have you made much progress since?
|01-27-2014 09:19 AM|
I'm amazed how long this original thread is.
I just reread my last post on this thread (we have a new adrenal fatigue thread because this one got too long for the server) and we were talking about chemo drugs. I've since found out that a chemo drug is used to end pregnancies that aren't where they should be (ectopic) and it got me wondering where else chemo drugs are used besides cancer treatment... Interesting.
|09-11-2013 01:26 PM|
In response to "The Adrenal Fatigue Thread"
I was amazed after i read your post. I too have Adrenal Fatigue, and just finished my first appt (after my saliza test results) with Dr. Neville. It seems you and I are reading from the same book. All of your test results and medications he recommended are very much the same as mine.
I've been on a journey now for almost 20 years trying to figure out some of my issues, the biggest one being weight gain or inability to loose weight. No matter what do, extreme exercise, low calories, etc. nothing seem to work. Although, while doing this type of extreme physical activity 6 days a week for the past 15 years, I've damaged my adrenal glands even more. I'm excited to know, there is hope to feeling better. Some of my symptoms are; anxiety, depression, hair falling out, foggy thinking, light headedness, dehydration, heart palpitations, weight issues, etc.
For the past 10 years, I've only ate a whole food diet, so that won't have to change much. Dr. Neville and I discussed my exercise program. I didn't think I could go without any exercise at all, so we compromised. I'll be shortening duration of training and replacing my strenuous routine with a more relaxing walk or stationary bike type of exercise. No more spinning classes, circuit and interval training, or running for me. I'll still maintain my weight training regime, but perhaps not so heavy or frequently.
No way to eliminate my stressful job at the moment, so that I'll just to deal with. I'll need to work on not letting things stress me out too much and learn to roll with the punches. Just do your best and let the cards fall where they will. Being that I'm in sales, that's easier said than done. Something to work towards...breath...relax.
All the medicaitons you listed are the same ones he put me on too. So, i'm taking all those plus my regular mult vitamin, vitamin c, b complex, selenium, thyroid complex, vitamin e and kelp. I noticed a big difference when I started taking kelp. You're right we need lots of salt and kelp has really help replace alot of the iodine my body was lacking. So, in actually it's not the salt that you need, it's the iodine it possess. The best form of iodine can be found in a unrefined salt product. Much like the one you mentioned. I had a iodine test taken and I was only 50% to capacity. Normal levels should be around 90%.
In addition to seeing Dr. Neville, I also see Arlene Curley from the Greenshire Art Consortium. She is a Reiki Master and works on adrenal glands too. She's wonderful and I would highly recommend seeing her as another part of your adrenal routine. She is affiliated with the Clymer Center and had originally recommeded I see Dr. Neville.
I'm interested in seeing more posts from you and read about your progress, and I'll do the same.
|10-23-2009 02:42 PM|
|georgia||Hi! I just noticed this thread has surpassed 2,000 posts, and typically, we need threads to stay under 2K posts or server can get cranky. Please feel free to start a new thread and link back to this one in the OP. Thanks so much, and sorry for the inconvenience!|
|10-23-2009 12:36 PM|
I think I'm getting lost - my head is spinning.
What does that imply about the chemo drugs? That I could have somehow been exposed to this & therefore my build up of androstenedione could be because it's not converting to estrone? My mother never took chemo drugs, nor have I.
We can definitely make a spin-off thread, but I have no idea what to title it...all of this pathway talk if Greek to me.
|10-23-2009 11:57 AM|
so... i'd start digging to see if there are tests to determine genetic mutations in the steroid hormone pathway that you can take to find out exactly which one (if any) you have. or see if there are tests for other metabolites downstream from androstenedione to see if there are other pathways... i'm not sure if these hydroxylases are enzymes that one can take orally.
what i did learn in this digging is that some of the chemo drugs for breast cancer therapy try to suppress the conversion of androstenedione to estrone.
should we spin off your steroid hormone pathway discussion into its own thread? or do you think this still belongs in this gigantic thread?
|10-23-2009 11:50 AM|
|Goddess3_2005||Can someone tell me if perifiral neropathy is part of this? I have just been diagnosed with this and I have numbness in my face, neck and upper back and toung that has been undiagnosed as of yet..|
|10-23-2009 10:57 AM|
ETA: correction, I think I'm thinking of Entero-Labs for stool testing...
|10-23-2009 10:44 AM|
I am jumping in here because I read some posts about people using Diagnos-Techs for panels. I am going to get a stool test for my son, and I am trying to decide between Genova or Diagnos-Techs. I know this is different, but does anybody have an opinion on that?
|10-23-2009 10:37 AM|
What bothers me more is that Dd2 seems like she could have also inherited this. She's 6.5 yrs old now & ever since she was maybe 2 or 3 yrs old, she's had nose hairs, a slight dark mustache & is definitely more muscular than her older sister. her leg hair is also darker & thicker than what seems more common.
I've always felt that Dd1 was the one who got the short stick as far as adrenal health, but maybe Dd2 is even worse off.
I need to know that there is a more holistic treatment than glucocorticoids.
|10-23-2009 09:45 AM|
bluets, I love you!!
Thank you SO much for explaining this to me.
|10-22-2009 11:54 PM|
so the conversion goes like the sketch in my ugly picture at https://dl.getdropbox.com/u/1907016/steroidhormones.png
(a more scientific view at http://www.genome.jp/kegg-bin/show_p...ko00140+C00410)
adrenal hyperplasia simply means that the adrenals aren't functioning properly to kick out the hormones that they govern. that is, there are some congenital hyperplasias that inhibit the hydroxylases (in the cytochrome P450 complex) in this pathway. cholesterol is a huge 27-carbon molecule, and it takes some chopping to whittle it down to the 18-carbon compound like estradiol. examples of the most commonly known ones are at http://en.wikipedia.org/wiki/Congeni...al_hyperplasia
(and since these are mutations, there are "easy" genetic screens/tests that can be done to detect those mutations)
recall also that the adrenal gland kicks out 3 different steroid hormones: cortisol (from the middle layer of the adrenal cortex), aldosterone (from the outer layer of the adrenal cortex), and the androgens (from the inner and middle layers of the adrenal cortex). androgens are converted to the highly potent hormones out in the peripheral tissues, not in the adrenal gland.
Metasequoia - it seems like there must be a dysfunction in the metabolism of androstenedione, particularly leading towards estrone (http://www.genome.jp/kegg/pathway/ko/ko00150.html) - ergo, there could be a blockage in the enzyme function inhibiting the breakdown. you could have overactive enzymes that cause it to break down into adrenosterone or 3-glucuronide instead of heading along to estrone. (or you could have an underactive enzyme that breaks it down into estrone)
|10-22-2009 09:45 PM|
I posted this in H&H too:
I was rereading Chronic Fatigue Unmasked 2000 by Dr. Poesnecker (who trained my ND) & this paragraph stuck with me:
|10-21-2009 11:14 AM|
|Metasequoia||Oh, and Androstenedione is used by body builders & athletes to build muscle and I seem to be able to build A LOT of muscle in a very short amount of time. I have a ton of definition, especially in my arms & I only started working out early this summer.|
|10-21-2009 11:13 AM|
I did a Diagnos-Techs male hormone panel a couple of weeks ago & the results are as follows:
DHEA - 1 - Depressed - Reference range: 3-10 ng/ml
Progesterone - 166 - Reference range: 100-300 pg/ml
Androstenedione - 380 - Reference range: 125-274 pg/ml (!!)
Testosterone - 16 - Reference range: 5-7 pg/ml - 8-20 pg/ml (marked as "normal")
Estrone - 12 - Reference range: 30-58 pg/ml
DHT - 15 - Reference range: 15-75 pg/ml
My results fall into these reference ranges according to age:
Testosterone (male): >70 years (15-45 pg/ml)
Dihydrotestosterone (DHT) (Male): not on the chart - closest range is 22-72 pg/ml for ages 30-39 yrs. (I guess that means mine isn't abnormally high.)
Androstenedione (Male > 15 years): 351-450 pg/ml is the "Borderline High" range - normal is 151-350 pg/ml - for a male over 15 yrs. Mine was 380 pg/ml - so mine is high even for a man.
Androstenedione (Female > 15 years): 275 - 400 pg/ml is the "Borderline High" range, normal is 125-274 pg/ml for a female over 15 years of age. Again, mine was 380 pg/ml.
Estrone (Female): Mine was 12, clearly VERY low.
38-68 pg/ml - 40-49 yrs
26-64 pg/ml - 50-59 yrs
35-65 pg/ml - > 60 yrs
I tested on cycle day 21, which was when the test is supposed to be taken. My cycle has been 31 days almost like clockwork & here we are on CD 36 with no period yet. I hope this hasn't thrown off my test.
SO, I haven't spoken to my ND yet, but I'm not sure what this all means. We did the male hormone panel for a few reasons. I tend to be fairly hairy - have been since my pre-teens. Recently my hair began thinning (not noticeably to anyone else) right at the front of my scalp, only in the middle. High levels of Dihydrotestosterone, or DHT, can cause thinning and baldness. That's what's to blame for male pattern baldness in men & in women - usually with PCOS. But my DHT doesn't appear to be high.
My estrone appears to be quite low - not sure how this is supposed to relate to where I was in my cycle, but it's not even in any of the reference ranges.
My Androstenedione is outrageously high. I don't know what this means. Here's what Androstenedione does in the body:
Also listed, I've read that high levels of androstenedione can be caused by adreno-cortical tumors and adrenal hyperplasia. Ugh, this is when I should stop Googling.
I'm confused because my testosterone isn't really high even though my adrostenedione is. I think that the high level of androstenedione could explain my sensitivity to carbs & sugar (insulin response.) Sounds like a PCOS issue.
I hope my ND has calming things to say about this.
|10-21-2009 10:27 AM|
Supplemental DHEA has the risk of causing masculanizing effects. Pregnenolone is much less likely to cause this.
|10-21-2009 06:14 AM|
Woe... I have only made it to page 7 so far... Lots of great information.
I am waiting for my saliva test results right now. Since I have hypo, I suppose I likely have AF as well.
Since my hypo ws found due to secondary infertility, we have had to use nfp until my levels get better. (Tough, when we hve hoped for a baby for years.) Could anyone give me an idea of what will happen if I indeed have AF. Does it mean more nfp while I take cortisone or what.... From what I understand, many people take a year until they can wean of f of the cortisone, and I am not getting any younger... This is really messing with my head right now.
|10-19-2009 09:04 PM|
I've found Dr. Wilson's products to be very helpful (he's the man who coined the term and the diagnosis for "adrenal fatigue" - http://www.adrenalfatigue.org
Additionally this e-book has helped me out a lot:
|10-19-2009 12:51 PM|
|dhammamama||I'm curious-- for those taking pregnenolone, what dose are you using? My dhea is very low, and I'm on RX topical, but wondering if oral pregnenolone might be a better choice?? Or maybe oral dhea..... ?|
|10-14-2009 03:42 PM|
|dosmilagros||I actually just hung up with him. He's very calming. I'm struggling with figuring out which doctor I want to be the "lead" doctor on this. I definitely like him but I always worry about how to know if his way is the "right" way or best way for me. (Can you tell I've had some bad doctor experiences!). It also makes me a little nervous to never actually meet him and him me. But he definitely seems to know what he's talking about and has a lot of patients with similar issues. He definitely gives me hope, which is what I need right about now......|
|10-14-2009 10:16 AM|
|10-13-2009 04:37 PM|
I'm starting to get quite anxious about my situation. I've joined the adrenal fatigue yahoo group and there's a woman on that who seems to know quite a lot and she has me a bit concerned. My ACTH came back high in bloodwork at my regular endo appt for my thyroid (they decided to test ACTH and cortisol). So that sent me to other doctors for the saliva testing. I believe that it is due to the strain on the adrenals and the pituitary is working extra hard to get the adrenals to do what they need to do. But my endo wants to test for Cushings and if that's negative, then other things. I don't know if I want to do the dexamethasone suppression test (for Cushings) because I'm concerned of artificially suppressing an already struggling system. I'm trying to get into another doctor for a second opinion on that but it's going to take time. As soon as my saliva tests are back, I want to start treatment, but people are starting to tell me that I need to do this testing first to rule things out. Like I said, I'm scared of the testing and its affect on my system. Has anyone else done this? I had been hoping to get advice from Dr. Neville on this but he hasn't responded to my email that I sent him with the health history that he requested.
I'm VERY anxious about my situation. I had been in a decent place for a few days but now I'm back to being in a bad place....
|10-13-2009 11:54 AM|
|10-13-2009 11:41 AM|
|sublimemommy||I'm still trying to browse through this! Wondering if virgin coconut oil has been discussed yet?|
|10-12-2009 12:28 AM|
|Vaquitita||yes they (my temps) were, i guess the more uneven temps is what got me wondering if it was too soon. the same company makes an adrenal organ capsule that i'd like to try. i think i'll back off the thyroid for now. and try again later.|
|10-11-2009 09:00 PM|
Hrm, I guess that could be a sign of adrenal stress if your temps were previously more even - were they?
OT: I hate when I type "you're" for "your" & get quoted on it.
|10-11-2009 06:16 PM|
|10-11-2009 09:41 AM|
The pregnenolone is *awesome* for brain fog. Give it a week or two, but I think you'll notice a difference (& check with your doc first.)
So you're off gluten, right? Gluten allergy seems to be really common in adrenal fatigue - hard to say which came first. I'm hoping that healing my adrenals will heal my food allergies - though I'll never eat gluten again.
Do you think your son might have sleep apnea? Not to sound alarmist, but it could be dangerous. Have you mentioned it to Dr. Neville? If I ever bring something up about my kids, he usually has suggestions on how to help. Does it wake your son? It obviously affects your daughter, which isn't good for her adrenals, in the long run.
What if you let her sleep in the other room alone & you slept with your son (since he obviously still need that security) & you used some kind of ear plugs? Do you use any kind of white noise? We sleep with a fan just for the noise...
|10-10-2009 09:02 PM|
Metaseqoia - I wonder if he (Neville) was referring to me - I mentioned this thread! Did you take any glandular support (sorry if it's been mentioned, I don't recall). I'm wondering about the Mil Andregan - I've been many references to it elsewhere and I think Neville recommends it. Is that where there is actual adrenal tissue? Are there any concerns about using it?
It does sound like a long road, but I"m up for it and willing to do whatever I need to do to stop this assault on my adrenals. I already have hashi's and gluten sensitivty and endometriosis, so I don't need any more stress on my body! I've been working with my acupuncturist for the past week or so on stress, as well as getting back into my mind-body relaxation tapes. It's starting to help. My biggest problem right now is getting sleep. My 2 kids have been sleeping with me but they really interrupt my sleep (especially my 3 yr old who makes a "moaning" noise periodically through the night. Now I lay awake waiting for his next moaning incident and I can't sleep). We're working on getting them into their own rooms (am trying to have them share, but his noisiness wakes my daughter up). My older one (5 in December) has never slept alone and really hates it, so it's really hard to make this transition when I am completely sleep-deprived, have a hard time falling asleep, staying asleep and going back to sleep. I'm hoping we can get something figured out so I can start gettign some sleep. When I got 4 straight hours on Thursday night, I felt almost like a new person on Friday. Can't even imagine what 8 straight hrs would be like!
|10-10-2009 02:44 PM|
|chlobo||I have not tried pregnalone. I have a followup with my ND next week. I'll ask her about it. The other things we tried seemed not to help.|
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