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Discussion Starter · #1 ·
Synagis (palivizumab) is manufactured by MedImmune and has been around for a couple of years. It is basically synthetic immune globulin, as I understand it. It is given to those babies at high-risk of getting serious respiratory syncytial virus (RSV). These babies used to get immune globulin infusions which were very painful and took hours in the hospital each month, but now they can "just" get this one shot. <img alt="" class="inlineimg" src="/img/vbsmilies/smilies/rolleyes.gif" style="border:0px solid;" title="rolleyes">:<br><br><div style="margin:20px;margin-top:5px;">
<div class="smallfont" style="margin-bottom:2px;">Quote:</div>
<table border="0" cellpadding="6" cellspacing="0" width="99%"><tr><td class="alt2" style="border:1px inset;">RSV is ubiquitous and highly contagious: approximately two-thirds of all infants are infected with RSV during the first year of life and almost 100% by the age of two.</td>
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As I understand it, RSV normally just gives cold symptoms if any symptoms at all. But in preemies, it can cause serious RSV disease, which is basically the lungs shutting down, and require hospitalization, etc. This is because preemies miss out on the transfer of immune globulins and other protective immune system boosters during the last trimester and are immune compromised as a result.<br><br>
The shots are given once every 30 days during the RSV season, which varies from year to year, but last year ran from October through May.<br><br>
My dd and ds got the shots every month because they were 32-weekers and it was their first winter. They were only a few months old at the start of the season. I know several children who were hospitalized with RSV, including our neighbors infant. So anyway, the threat felt "real" to me and I was given lots of scary brochures with photos of RSV babies hooked up to breathing tubes and looking teeny and pale, and it went scared the daylights out of me, not wanting dd or ds to have to endure one more second in a hospital.<br><br>
So the reason I'm posting now, is I'm wondering what IS known about Synagis. It's not a vaccine technically, but I thought some of you might know about it anyway - I couldn't find any threads on Synagis. I've never heard anything but good about it, but of course that was true of all other vaccines until I started doing research. I wish I'd been clear-headed enough to evaluate this last winter, but "when you know better you do better".<br><br>
Any insights, info appreciated.<br><br>
[Edited for spelling.]
 

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I found this old thread on RSV that may be of help:<br><br><a href="http://216.92.20.151/discussions/showthread.php?s=&threadid=33032&highlight=respiratory+syncytial+virus" target="_blank">http://216.92.20.151/discussions/sho...yncytial+virus</a>
 

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Discussion Starter · #4 ·
gilnikche thank you for the link to that thread - very interesting to read all about RSV!<br><br>
I guess I'll have to keep digging though to learn more about Synagis. There's not a lot of information about this "vaccine" (for lack of a better word) - none of the books I've read have much on it and sites like this tend to focus on the real vaccines (for understandable reasons <img alt="" class="inlineimg" src="http://www.mothering.com/discussions/images/smilies/smile.gif" style="border:0px solid;" title="smile"> )<br><br>
I'll post here if I find anything.
 

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Have you tried a Google search? I find most of my info throught this search engine.<br><br><a href="http://www.google.com" target="_blank">www.google.com</a>
 

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Discussion Starter · #6 ·
Yes. I have not found very much after some light digging. As I wrote I'll post back here if I find anything more substantive.
 

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Try searching PubMed at <a href="http://www.ncbi.nlm.nih.gov/PubMed/" target="_blank">http://www.ncbi.nlm.nih.gov/PubMed/</a><br>
for Synagis or palivizumab.<br><br>
You can at least read the abstracts of most of the papers, some of them have on-line full text. If you are associated with a university, you might have access to more on-line articles through the university library.<br><br>
I've never heard anything bad about Synagis either. My son was born at 30 weeks in May 2000 and had it his first winter. I really think he would have been fine without it. He was nursing and wasn't around other kids very much. But I guess hindsight is 20/20.<br><br>
Good luck with your search.<br><br>
Linda
 

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Well, this is interesting: it turns out that a lot of cases of what they thought were RSV-induced diseases aren't actually caused by RSV after all, but by a newly-discovered virus. I don't know what that means for Synagis.<br><br><a href="http://content.health.msn.com/content/article/73/89022.htm" target="_blank">MSN health article on human metapneuomovirus</a>
 

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Discussion Starter · #9 ·
Oh my lord. <img alt="" class="inlineimg" src="http://www.mothering.com/discussions/images/smilies/yikes.gif" style="border:0px solid;" title="EEK!"><br><br>
I'll be interested to read more about this new virus vis a vis Synagis. Ugghh...
 

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Here's some info I found on a search,<br><br><a href="http://www.bmjpg.co.uk/books/ebp/chapters/chapter26update.htm" target="_blank">http://www.bmjpg.co.uk/books/ebp/cha...er26update.htm</a><br><br>
Christine
 
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