My nephew is autistic (he has a diagnosis of PDD-NOS) and he has never had a vaccine. Medical journals before the 20th century have documented cases of autism. This is a neurological disorder that is often genetically based--so there are often clusters of autism or related neuro disorders within family lines.<br><br>
Here is some info I found:<br><br>
How long have Autism Spectrum Disorders existed?<br><br>
Dr. Leo Kanner, a physician at Johns Hopkins Hospital, published the first paper describing autism in 1943. At virtually the same time, an Austrian psychologist, Hans Asperger, described a similar group of patients. Although ASD has been recognized as a medical condition only in modern times, there are many historical accounts pointing to the existence of autism well before the 20th century.