I've been on Prozac for depression since '99. My baby is almost 5 months old, and I continued taking Prozac during my pregnancy and while I am nursing. I wanted to quit so badly, but my doctor and my OBGYN both strongly advised against it. DD is doing beautifully, she was born healthy and is a happy, thriving child, growing well, sleeping well, and generally a joy to be around. I can't say anything about the scientific part because I am not educated enough when it comes to that, but in my own experience, Prozac hasn't had a negative effect. And it has one major advantage: it keeps me healthy. And a healthy mom is what my baby benefits from the most, right?