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Just wanted to let all you wonderful ladies know that I keep you in my thoughts daily. Unfortunately, I didn't discover the MDC boards until just a couple months ago, otherwise I would have been here too!<br><br>
Anyway, this post is to offer some encouragment to all of you, but especially those who have been TTC for more than a year or two. After 5 years TTC with PCOS we are expecting a daughter in September!<br><br>
We were at the end of the road, activly researching adoption, and had pretty much given up on getting pg. Our journey included clomid, glucophage, hcg injections, progesterone (oral & suppository), 4 failed IUI's, and a failed ovarian drilling/hysteroscopy/hysterosalpingogram/lap. We didn't do injections or IVF simply because we could not afford to & still adopt if we were unsuccessful.<br><br>
Now the advice for everyone with PCOS out there....talk to your RE about glucophage if you havn't done so already! I <img alt="" class="inlineimg" src="http://www.mothering.com/discussions/images/smilies/love.gif" style="border:0px solid;" title="love"> glucophage! My last doc (an GYN actually with some infertility background) was finally the one who agreed to prescribe glucophage for me as a long term thing.<br><br>
For years I'd tried to talk my provider's into letting me try just glucophage by itself, but nobody ever would. <img alt="" class="inlineimg" src="/img/vbsmilies/smilies/eyesroll.gif" style="border:0px solid;" title="roll"> If I wasn't combining it with Clomid they wouldn't give it to me. I knew it was doing something since the Clomid did not work AT ALL without it, and the only time I ever lost weight was when I was taking the glucophage.<br><br>
Anyway, this wonderful local GYN agreed to let me try it out. I was actually doing it to loose weight, and figured if I happened to O that would be great to (we were starting adoption stuff remember.) I was on 1500 mg (one 500 mg tab w/each meal). I started in January 03. In August 03 I had my first cycle in over a year. August-September I had a 49 day cycle. September-October I had a 42 day cycle. October-November I had a 36 day cycle. November-December I had a 30 day cycle & got pregnant with DD.<br><br>
I was keeping track of my cycles & weight on a calendar, but not charting & not timing sex at all. We got our bfp on 1/8 and I was slowly tapered off the glucophage until week 12 when I stopped it all together. During that year, not only did I start cycling on my own, but I lost almost 40 lbs with absolutly no change to my diet or exercise.<br><br>
Needless to say I *strongly* encourage anyone with PCOS who is ttc to speak with thier provider about glucophage. I know how very lucky we are, but I also know that I wouldn't be pg now if I hadn't keep at it until I found a doc who was willing to let me try what I felt would work.<br><br>
Here's lots of <img alt="" class="inlineimg" src="http://www.mothering.com/discussions/images/smilies/dust.gif" style="border:0px solid;" title="dust"> for everyone...<br><br>
Many prayers & positive thoughts,<br><br>
Holly
 

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Congratulations! What an encouraging story. <img alt="" class="inlineimg" src="http://www.mothering.com/discussions/images/smilies/luxlove.gif" style="border:0px solid;" title="throb">
 

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thank you thank you thank you thank you thank you!!!!!!!<br>
We have been ttc for 11 months now and my OB/Gyn finally prescribed me Metformin. I've been on it for 1 1/2 weeks now. Plus I just started Provera to get my cycle going. I have normal periods 29 days apart but for some reason I haven't been able to get pregnant! I have 1 dd who is 3 1/2 so this is considered a secondary fertility issue. Right now I am cd39 for some reason-not pregnant. They say maybe I didn't ovulate this month. But as soon as I am done with the provera and my period comes I am taking clomid. i am so excited. I hope it works! Thanks for sharing your info!
 

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Congratulations Holly! I, too, hav a similar story. We had been ttc for almost 2 years when I was finally dx with PCOS and prescribed glucophage. 3 months later I was pg without any other medications or interventions. Before that we had tried 1 iui, 2 ivf/icsi (my dh was dx with low sperm count also) and 1 fet. All wer bfn. I even had a doctor tell me that I had an anembryonic sac (blighted ovum) because according to my dates they thought I was 8w pg when I was only 5w. I had been charting and using an opk so I knew when I ovulated and when I concieved. He said I would need a D&C. My baby is now 5 months old. I believe glucophage was the miracle we were searching. Even if it doesn't help you get pg, it still may be very important to take for your general health.
 

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Congratulations, Holly! Best wishes for you and your family.<br><br>
I hope you don't mind, but I had alot of questions about this drug, but couldn't get any answers from anyone. I am wondering (mostly because I was prescribed Metformin the month before we got our BFP, but I never had it filled because my doctor refused to answer any of my questions) do you take the glucophage again after you give birth? What dangers would it pose to your baby, while you taper off, if any? I think I read that you cannot take it while breastfeeding, either.
 

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I continued to take glucophage through my first trimester because there are studies that show it reduces the high risk that women with PCOS will miscarry. I think the m/c rate in women without pcos is around 15% where the risk with pcos is upwards of 30%. I actually went against my OB to take the glucophage while pg. He would not prescribe it for me so I went back to my RE and got a script for it. I did tell my OB I was taking. At 12 weeks I just stopped, no tapering off. I have also recently learned that some doctors say it's safe to take while breastfeeding. Check out the pcos websites like PCOSA and Soulcysters.
 
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