FDA approved use doesn't impress me much. I mean have you seen the commercials for a certain allergy medication, for example, that claims they are the only one "FDA approved" for both indoor and outdoor allergies. As if the other ones that have only been approved for indoor, but help you with outdoor too, shouldn't be used for your "outdoor" allergies. I don't know, it doesn't matter to me personally. Many drugs have other uses besides what they are FDA approved for. I want my doctors to be able to use drugs for off-label uses. What does matter to me is that the benefits outweigh the risks and that patients are made aware of the risks. Which has been the problem with Cytotec IMO. Doctors use it without telling women the real risks of the drug.