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I find this really fascinating. I think, I hope, that more people are realizing that obesity just isn't a choice. That there really are some strong genetic factors involved. I have a feeling in 20-30 years, people are going to look back at the "well, you could be thin if you tried hard enough" similar to the way we look at ads from the 50s where physicians promoted cigarettes. (OK, not the best analogy but I'm tired.) <img alt="" class="inlineimg" src="/img/vbsmilies/smilies/dizzy.gif" style="border:0px solid;" title="Dizzy">:<br><br><a href=";_ylt=AmxOTxoIgx9z5UdP0h1YmH7VJRIF" target="_blank"></a><br><br><div style="margin:20px;margin-top:5px;">
<div class="smallfont" style="margin-bottom:2px;">Quote:</div>
<table border="0" cellpadding="6" cellspacing="0" width="99%"><tr><td class="alt2" style="border:1px inset;">They studied 707 severely obese (average BMI 51.2) patients who had gastric bypass surgery. Blood samples from the patients were analyzed for two common single nucleotide polymorphisms (SNPs) previously found to be associated with obesity. SNPs are variations caused by alteration of single building block of DNA.<br><br>
The researchers found that about 21 percent of the patients had two copies of one obesity-related SNP, 13 percent had two copies of the other SNP, and 3.4 percent had two copies of both SNPs.<br><br>
There was no significant BMI difference between patients with two identical copies of either one of the SNPs and those without two identical copies. However, patients with either two copies of both SNPs, or two copies of one and one copy of the other SNP, had much higher BMIs than other patients. Less than 20 percent of the patients in the study had these genetic features.<br><br>
The findings were published in the March issue of the journal Archives of Surgery.<br><br>
It's not known how these SNPs may influence obesity, but the researchers said their findings indicate "that the two genes may interact, suggesting that the physiological pathways in which each is involved may be linked in some way."</td>
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