We keep ours set at 60 year round, but then we don't get snow.
The animals don't seem to have a problem with it so long as they have somewhere warm to go... for us that means we leave blankets on the couch, and they're welcome to the bed, etc. Our older cat has even taken to sleeping on the heating grate that's right above the pilot light for the furnace. And we have several windows where the sun shines in and they can lie in the sun.