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So I had DS tested with the Organix test from Metagenics (using Direct Labs to bypass a doctor). I don't quite understand a lot of the results and am wondering if there are dietary changes we can do, since I'm not sure about how to obtain some of the supplements recommended in a form he would take. I will attempt to paste them here:
Findings Intervention Options Common Metabolic Association
Carbohydrate Metabolism: Pyruvate Lipoic Acid, High B1, B2, B3, B5 Glucose oxidation
CoQ10, Lipoic Acid, B1, B2, B3, B5 a-Ketoglutarate Very High Citric acid cycle
CoQ10 Hydroxymethylglutarate High HMG-CoA reductase inhibition
B-Complex Vitamin Markers
Lipoic Acid, B1, B2, B3, B5 a-Keto-B-Methylvalerate High Impaired Isoleucine metabolism
Biotin, B2 ß-Hydroxyisovalerate High Impaired Isoleucine metabolism
Methylation Cofactor Markers
No Abnormality Found
Neurotransmitter Metabolism Markers
Magnesium, Immune support Quinolinate Very High Receptor agonist
Oxidative Damage and Antioxidant Markers
Vitamin C, Vitamin E 8-Hydroxy-2-deoxyguanosine High DNA oxidation product
Detoxification Indicators
N-acetylcysteine, Glutathione,
Hepatic support
Glucarate High Hepatic Phase I and II detox
Bacterial - General
Glycine Hippurate High Hepatic Phase II conjugation
Probiotics p-Hydroxyphenylacetate High Intestinal Bacterial Overgrowth
L. acidophilus / general bacteria: No Abnormality Found
Findings Intervention Options Common Metabolic Association
Carbohydrate Metabolism: Pyruvate Lipoic Acid, High B1, B2, B3, B5 Glucose oxidation
CoQ10, Lipoic Acid, B1, B2, B3, B5 a-Ketoglutarate Very High Citric acid cycle
CoQ10 Hydroxymethylglutarate High HMG-CoA reductase inhibition
B-Complex Vitamin Markers
Lipoic Acid, B1, B2, B3, B5 a-Keto-B-Methylvalerate High Impaired Isoleucine metabolism
Biotin, B2 ß-Hydroxyisovalerate High Impaired Isoleucine metabolism
Methylation Cofactor Markers
No Abnormality Found
Neurotransmitter Metabolism Markers
Magnesium, Immune support Quinolinate Very High Receptor agonist
Oxidative Damage and Antioxidant Markers
Vitamin C, Vitamin E 8-Hydroxy-2-deoxyguanosine High DNA oxidation product
Detoxification Indicators
N-acetylcysteine, Glutathione,
Hepatic support
Glucarate High Hepatic Phase I and II detox
Bacterial - General
Glycine Hippurate High Hepatic Phase II conjugation
Probiotics p-Hydroxyphenylacetate High Intestinal Bacterial Overgrowth
L. acidophilus / general bacteria: No Abnormality Found