Hi I am pregnant with number 3. My sister and I both have PCOS. Her weight is much higher than mine (225 lbs her, 160 lbs me) so the fertility problems for her are worse. She has one daughter who was 6 in April and she has been trying for a second for 4.5 years. She really doesn't ovulate at all. She has only tried Metformin, nothing else. I had my son right after she started trying. He was conceived using herbs and diet. My daughter was born 21.5 months later, conceived with Metformin. Both were conceived the first month I managed to induce ovulation. I had been using Metformin again since January but not trying and it wasn't bring on ovulation. In April I tried soy isoflavones which can be used like Clomid and I ovulated. We started trying this month with Metformin, soy and natural progesterone cream and we concieved again first try. So I have very good fertility success despite the fact that I don't ovulate unless I push it along. I have recommend my sister try the soy isoflavones but she is also waiting on domestic special needs adoption and doesn't want to mess that up. I called her to tell her today because we talk every day and I just wanted to get it over with. I didn't think she'd be happy or anything, of course it hurts her. But I at least thought she could muster a congratulations or ask me if I'm excited or anything. All she said was that God isn't fair. Then she changed the subject to her computer game she was playing. I know she is sad but I don't know what to do. I feel like there is a wall between us now. With my daughter she was sad but not too upset because she still thought she'd be able to have more. I think she is angry and upset and like I said I understand that. But we have always been close (I don't really have any friends) and now I feel like I have no one to share anything with. I feel so distanced from her like I can't call her anymore or mention anything about my life. I guess there is nothing I can do to make things better, I didn't do anything wrong to begin with.