Metcalf TJ, Irons TG, Sher LD, Young PC. Simethicone in the treatment of infant colic: A randomized, placebo-controlled, multicenter trial; Pediatrics 1994; 94:29-34
This study shows that in colicky babies no difference in gasiness occurs following mylicon (brand name simethicone). I'm sure other studies show the same thing...i just don't have time to pubmed it right now. If it works for you use it, the research doesn't support it though.