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Discussion Starter #1
<p>Pertussis being one of the more difficult VPD's to control, I usually check in on updates about local/regional epidemics and news associated with the disease. This morning I found a few things of interest. If anyone finds any new interesting updates about B. Pertussis that might not warrant starting an entire thread in VOS, maybe we can keep this thread going with new updates related to vaccine efficacy, diagnosis, surveillance, epidemics, new research, possible new vaccines, etc.</p>
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<p><span style="text-decoration:underline;"><strong>Diagnosis/Surveillance</strong></span></p>
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<p>Some of the stock/finance sections of the news are reporting that the FDA has recently approved a new diagnostic test that provides results within 60 minutes. Depending on its accuracy (haven't checked into it yet, but I will update if I find anything new), this could be great news for babies for whom a timely diagnosis can be a lifesaver.</p>
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<p>FDA Clears Meridian Illumigene Pertussis Test</p>
<p><a href="http://cdnwww.genomeweb.com/clinical-genomics/fda-clears-meridian-illumigene-pertussis-test" target="_blank">http://cdnwww.genomeweb.com/clinical-genomics/fda-clears-meridian-illumigene-pertussis-test</a></p>
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<p>I also saw where the Council of State and Territorial Epidemiologists (CTSE) updated some of the criteria for surveillance cases, to include infant apnea with a cough of any duration, in order to get a more accurate idea of "the burden of disease among infants." (PDF)</p>
<p><a href="http://c.ymcdn.com/sites/www.cste.org/resource/resmgr/PS/13-ID-15.pdf" target="_blank">http://c.ymcdn.com/sites/www.cste.org/resource/resmgr/PS/13-ID-15.pdf</a></p>
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<p><span style="text-decoration:underline;"><strong>Outbreak Data</strong></span></p>
<p>It's tough finding out where 2014 epidemics might be emerging but I did find an updated report of the past two years.</p>
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<p>It seems in many areas where it has been bad recently, pertussis is declining a bit e.g. from 2012 to 2013 (as expected with its typical 3-5 year cycles).</p>
<p>Updated outbreak report from 2012-2013 (PDF).</p>
<p><a href="http://www.cdc.gov/pertussis/downloads/pertussis-surveillance-report.pdf" target="_blank">http://www.cdc.gov/pertussis/downloads/pertussis-surveillance-report.pdf</a></p>
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<p><strong>If anyone finds 2014 news, please share!</strong></p>
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<p>I am expecting in July and planning to get Tdap in my 3rd tri. We had just a handful of confirmed cases in my area, but the rule of thumb is that confirmed cases represent only about 10% of total cases, so I think it's safe to assume that pertussis is in my area. We haven't had any major outbreaks in recent years, although last year's 166 cases in my state was considered the biggest outbreak in decades.</p>
 

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<p>Here are a few outbreaks being reported this year:</p>
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<p>Montana</p>
<p><a href="http://www.beartoothnbc.com/news/1677756191-7-cases-of-pertussis-confirmed-recently-in-helena-area.html" target="_blank">http://www.beartoothnbc.com/news/1677756191-7-cases-of-pertussis-confirmed-recently-in-helena-area.html</a></p>
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<p>Long Beach, CA:</p>
<p><a href="http://abclocal.go.com/kabc/story?section=news/local/los_angeles&id=9513734" target="_blank">http://abclocal.go.com/kabc/story?section=news/local/los_angeles&id=9513734</a></p>
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<p>Dr. Oz, who sometimes gets criticized for supporting vaccine critics/skeptics, recently (April 22) urged vaccination among adults in light of recent measles and mumps outbreaks, and the rise in cases of whooping cough epidemics.</p>
<p><a href="http://www.doctoroz.com/episode/health-alert-3-deadly-diseases-making-comeback#comments" target="_blank">http://www.doctoroz.com/episode/health-alert-3-deadly-diseases-making-comeback</a></p>
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<p>Here's a new collaborative study on pertussis evolution and adaptation in the post-vaccine era. It's an open access article, full text is free, published 22 April 2014. The authors investigated the traits of 343 different strains of pertussis from around the world to understand how pertussis adapts and what factors drive these changes. They observed that the whole cell vaccine did have a significant effect on the rate of adaptation.</p>
<p><a href="http://mbio.asm.org/content/5/2/e01074-14" target="_blank">http://mbio.asm.org/content/5/2/e01074-14</a></p>
 
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