[preemiemamarach]

I will cross-post in Allergies, but thought I might find other parents here who have BTDT since you guys are more likely to have hospitalized kids.

DS was hospitalized last week for an IV iron infusion. He had an anaphylactoid reaction in the 3rd hour of his infusion- he went from fine to nearly needing intubation within 62 seconds. I have actually seen patients die from anaphylaxis, so I kind of lost my mind. We know it was anaphylactoid, not anaphlyactic, because his IgE didn't increase (although he did have some major shifts in his white cell percentages).

He is about to be admitted again for some additional infusions, and we are trying to determine whether he had a toxic reaction to the iron, or an allergic reaction to the sugar source. So far, nobody can tell us (outside of skin prick testing, which we can't do this soon after a reaction) what tests to run. The sugar in the IV solution will most likely be in the other meds he gets this next go-round, and we need to figure out what/how to monitor. It's doubly perplexing because his reaction happened so late.

If anyone else has been through this type of thing, what was monitored in subsequent infusions? We can certainly premedicate him with benadryl and steroids, but we'd love to know if there is a way we can avoid putting him through this again.

Thanks!

 

[ShaggyDaddy]

could it be latex? There are reported cases of light, early respitory ONLY (sometimes unnoticable) and late high exposure symptoms with latex... and of course that would be more common than iron, or even sugar source (unless there were protiens in the sugars)

In this case the man was under with no apparent exposure symptoms for Thirty-five minutes
http://sciencelinks.jp/j-east/articl...03A0558581.php

 

[preemiemamarach]

Thanks, SD (and I must say, you have the coolest collection of kids' names EVER). This is actually something we considered, even though the hospital is latex-free. The pharmacy actually went through and traced back all of the med caps and bags to make sure there was no latex in any of them.

Thanks for the link, that's actually really helpful- all of the doctors were completely perplexed that it happened so late. I've been looking for data on incidence of late anaphylactoid reactions, so this will help.

 

[2boyzmama]

No info for you, but how scary!!!

I had an anaphylactic reaction to penicillin as a toddler, very scary (says my mom, at least!).

Shudder...very scary!!!